Glucose labeled with 14c in c 1 and c 6
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Glucose labeled with 14C in C-3 and C-4 is completely converted to acetyl-CoA via glycolysis and the pyruvate dehydrogenase complex. What percentage of the acetyl-CoA molecules formed will be labeled with 14C, and in which position of the acetyl moiety will the 14c label be found?
a) 100% of the acetyl-CoA will be labeled at C-1 (carboxyl).
b) 100% of the acetyl-CoA will be labeled at C-2
c) 50% of the acetyl-CoAwill be labeled, all at C-2 (methyl).
d) No label will be found in the acetyl-CoA molecule
e) Not enough information is given to answer this question.